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Publikationer som ChEBI hänvisar till för kenpaullone. Visa hela publikationsregistret

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Publications in the selection

15 hits

Bibliografisk träff 2021-01-07

KLF4 inhibition by Kenpaullone induces cytotoxicity and chemo sensitization in B-NHL cell lines via YY1 independent.

Montecillo-Aguado M, Morales-Martínez M, Huerta-Yepez S, Vega MI.

Leuk Lymphoma · research support, non-u.s. gov't; journal article · DOI 10.1080/10428194.2020.1869960

Bibliografisk träff 2020-01-07

A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria.

Scott HL, Buckner N, Fernandez-Albert F, Pedone E, Postiglione L, Shi G, Allen N, Wong LF, Magini L, Marucci L, O'Sullivan GA, Cole S, Powell J, Maycox P, Uney JB.

J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.ra119.009699

Bibliografisk träff 2019-07-11

Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma.

Kitabayashi T, Dong Y, Furuta T, Sabit H, Jiapaer S, Zhang J, Zhang G, Hayashi Y, Kobayashi M, Domoto T, Minamoto T, Hirao A, Nakada M.

Sci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41598-019-46454-8

Bibliografisk träff 2018-07-23

A SIRT1-centered circuitry regulates breast cancer stemness and metastasis.

Shi L, Tang X, Qian M, Liu Z, Meng F, Fu L, Wang Z, Zhu WG, Huang JD, Zhou Z, Liu B.

Oncogene · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41388-018-0370-5

Bibliografisk träff 2018-03-26

Protective effects of kenpaullone on cardiomyocytes following H<sub>2</sub>O<sub>2</sub>-induced oxidative stress are attributed to inhibition of connexin 43 degradation by SGSM3.

Joo HC, Choi JW, Moon H, Lee CY, Yoo KJ, Kim SW, Hwang KC.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2018.03.166

Bibliografisk träff 2018-03-07

CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.

Teitz T, Fang J, Goktug AN, Bonga JD, Diao S, Hazlitt RA, Iconaru L, Morfouace M, Currier D, Zhou Y, Umans RA, Taylor MR, Cheng C, Min J, Freeman B, Peng J, Roussel MF, Kriwacki R, Guy RK, Chen T, Zuo J.

J Exp Med · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1084/jem.20172246

Bibliografisk träff 2017-11-10

Developmental effects of the protein kinase inhibitor kenpaullone on the sea urchin embryo.

Anello L, Cavalieri V, Di Bernardo M.

Comp Biochem Physiol C Toxicol Pharmacol · journal article · DOI 10.1016/j.cbpc.2017.11.001

Bibliografisk träff 2016-03-24

Small molecule-mediated up-regulation of microRNA targeting a key cell death modulator BNIP3 improves cardiac function following ischemic injury.

Lee SY, Lee S, Choi E, Ham O, Lee CY, Lee J, Seo HH, Cha MJ, Mun B, Lee Y, Yoon C, Hwang KC.

Sci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/srep23472

Bibliografisk träff 2015-12-30

The inhibitors of cyclin-dependent kinases and GSK-3β enhance osteoclastogenesis.

Akiba Y, Mizuta A, Kakihara Y, Nakata J, Nihara J, Saito I, Egusa H, Saeki M.

Biochem Biophys Rep · research-article; journal article · DOI 10.1016/j.bbrep.2015.12.011

Bibliografisk träff 2015-01-05

Downregulation of the KLF4 transcription factor inhibits the proliferation and migration of canine mammary tumor cells.

Tien YT, Chang MH, Chu PY, Lin CS, Liu CH, Liao AT.

Vet J · research support, non-u.s. gov't; journal article · DOI 10.1016/j.tvjl.2014.12.031

Bibliografisk träff 2014-05-27

Inhibition of CDK2 promotes inducible regulatory T-cell differentiation through TGFβ-Smad3 signaling pathway.

Gu H, Ding L, Xiong SD, Gao XM, Zheng B.

Cell Immunol · journal article · DOI 10.1016/j.cellimm.2014.05.004

Bibliografisk träff 2013-11-13

A pharmacological network for lifespan extension in Caenorhabditis elegans.

Ye X, Linton JM, Schork NJ, Buck LB, Petrascheck M.

Aging Cell · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/acel.12163

Bibliografisk träff 2006-03-01

The first metal-based paullone derivative with high antiproliferative activity in vitro.

Dobrov A, Arion VB, Kandler N, Ginzinger W, Jakupec MA, Rufińska A, Graf von Keyserlingk N, Galanski MS, Kowol C, Keppler BK.

Inorg Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/ic0511120

Bibliografisk träff 2005-04-12

New thiophene analogues of kenpaullone: synthesis and biological evaluation in breast cancer cells.

Brault L, Migianu E, Néguesque A, Battaglia E, Bagrel D, Kirsch G.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2005.02.010

Bibliografisk träff 1999-07-01

Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity.

Schultz C, Link A, Leost M, Zaharevitz DW, Gussio R, Sausville EA, Meijer L, Kunick C.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm9900570