CXCR2, as a key regulatory gene of HDP-PG-1, maintains intestinal mucosal homeostasis.
Yan D, Wei G, Ai Z, Song S, Zhang L, Dong N, Dou X, Shan A.
Int J Biol Macromol · journal article · DOI 10.1016/j.ijbiomac.2024.132025 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för SB225002. Visa hela publikationsregistret
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31 hitsCathelicidin boosts the antifungal activity of neutrophils and improves prognosis during <i>Aspergillus fumigatus</i> keratitis.
Hou X, Li C, Liu J, Yang S, Peng X, Wang Q, Liu C, Liu X, Luan J, Zhao G, Lin J.
Infect Immun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/iai.00483-23CXCL1-CXCR2 axis mediates inflammatory response after sciatic nerve injury by regulating macrophage infiltration.
Jiang S, Li W, Song M, Liang J, Liu G, Du Q, Wang L, Meng H, Tang L, Yang Y, Zhang B.
Mol Immunol · journal article · DOI 10.1016/j.molimm.2024.03.006IL-8 Triggers Neutrophil Extracellular Trap Formation Through an Nicotinamide Adenine Dinucleotide Phosphate Oxidase- and Mitogen-Activated Protein Kinase Pathway-Dependent Mechanism in Uveitis.
Shu Q, Zhang N, Liu Y, Wang X, Chen J, Xie H, Pan F, Zhao L, Ding X, Wen Y, Wang L, Xie W, Lu J, Su G, Peng H, Yang P.
Invest Ophthalmol Vis Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1167/iovs.64.13.19CXCR2 antagonism attenuates neuroinflammation after subarachnoid hemorrhage.
Luo X.
J Stroke Cerebrovasc Dis · journal article · DOI 10.1016/j.jstrokecerebrovasdis.2023.107266Targeting CXCL1 chemokine signaling for treating cisplatin ototoxicity.
Al Aameri RFH, Alanisi EMA, Oluwatosin A, Al Sallami D, Sheth S, Alberts I, Patel S, Rybak LP, Ramkumar V.
Front Immunol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.3389/fimmu.2023.1125948[CXCL1 induces the contraction of endothelial cytoskeleton and increases permeability in mouse cerebral endothelium bEND.3 cells by promoting protein kinase B phosphorylation].
Han Y, Dong Y, Li X, Xiong Q, Chen X, Li B, Wang H, Song C, Wu F.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · journal article; english abstractInvolvement of CXCL17 and GPR35 in Gastric Cancer Initiation and Progression.
Li Y, Liu A, Liu S, Yan L, Yuan Y, Xu Q.
Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms24010615Combining TMZ and SB225002 induces changes of CXCR2 and VEGFR signalling in primary human endothelial cells <i>in vitro</i>.
Urbantat RM, Jelgersma C, Vajkoczy P, Brandenburg S, Acker G.
Oncol Rep · research-article; journal article · DOI 10.3892/or.2022.8373Molecular insights into the microtubules depolymerizing activity of the IL-8 receptor B antagonist SB225002.
Goda AE, Sakai T.
Eur Rev Med Pharmacol Sci · journal article · DOI 10.26355/eurrev_202205_28869Chemokine (C-X-C motif) ligand 1/chemokine (C-X-C motif) receptor 2 autocrine loop contributes to cellular proliferation, migration and apoptosis in cervical cancer.
Sun J, Yuan J.
Bioengineered · research support, non-u.s. gov't; research-article; journal article · DOI 10.1080/21655979.2022.2036896CXCR2, a novel target to overcome tyrosine kinase inhibitor resistance in chronic myelogenous leukemia cells.
Kim JH, Lee SJ, Kang KW, Lee BH, Park Y, Kim BS.
Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2021.114658CXCL5/CXCR2 modulates inflammation-mediated neural repair after optic nerve injury.
Liu YF, Liang JJ, Ng TK, Hu Z, Xu C, Chen S, Chen SL, Xu Y, Zhuang X, Huang S, Zhang M, Pang CP, Cen LP.
Exp Neurol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.expneurol.2021.113711Rebound increases in chemokines by CXCR2 antagonist in breast cancer can be prevented by PKCδ and PKCε activators.
Erin N, Tavşan E, Akdeniz Ö, Isca VMS, Rijo P.
Cytokine · research support, non-u.s. gov't; journal article · DOI 10.1016/j.cyto.2021.155498IL-8/CXCR2 Signalling Promotes Cell Proliferation in Oesophageal Squamous Cell Carcinoma and Correlates With Poor Prognosis.
Inoue M, Takeuchi H, Matsuda S, Nishi T, Fukuda K, Nakamura R, Takahashi T, Wada N, Kawakubo H, Kitagawa Y.
Anticancer Res · journal article · DOI 10.21873/anticanres.14830WNT5A augments cell invasiveness by inducing CXCL8 in HER2-positive breast cancer cells.
Kim S, You D, Jeong Y, Yoon SY, Kim SA, Kim SW, Nam SJ, Lee JE.
Cytokine · research support, non-u.s. gov't; journal article · DOI 10.1016/j.cyto.2020.155213Chemokine Receptor CXCR-2 Initiates Atrial Fibrillation by Triggering Monocyte Mobilization in Mice.
Zhang YL, Cao HJ, Han X, Teng F, Chen C, Yang J, Yan X, Li PB, Liu Y, Xia YL, Guo SB, Li HH.
Hypertension · research support, non-u.s. gov't; journal article · DOI 10.1161/hypertensionaha.120.14698CXCR2 antagonist attenuates neutrophil transmigration into brain in a murine model of LPS induced neuroinflammation.
Wu F, Chen X, Zhai L, Wang H, Sun M, Song C, Wang T, Qian Z.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2020.05.124Participation of CXCL1 in the glial cells during neuropathic pain.
Moraes TR, Elisei LS, Malta IH, Galdino G.
Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2020.173039The CXCR2/CXCL2 signalling pathway - An alternative therapeutic approach in high-grade glioma.
Acker G, Zollfrank J, Jelgersma C, Nieminen-Kelhä M, Kremenetskaia I, Mueller S, Ghori A, Vajkoczy P, Brandenburg S.
Eur J Cancer · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejca.2019.12.005Inhibition of Aerobic Glycolysis Promotes Neutrophil to Influx to the Infectious Site Via CXCR2 in Sepsis.
Tan C, Gu J, Chen H, Li T, Deng H, Liu K, Liu M, Tan S, Xiao Z, Zhang H, Xiao X.
Shock · research support, non-u.s. gov't; journal article · DOI 10.1097/shk.0000000000001334Chronic inhibition of chemokine receptor CXCR2 attenuates cardiac remodeling and dysfunction in spontaneously hypertensive rats.
Zhang YL, Geng C, Yang J, Fang J, Yan X, Li PB, Zou LX, Chen C, Guo SB, Li HH, Liu Y.
Biochim Biophys Acta Mol Basis Dis · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbadis.2019.165551SB225002 inhibits prostate cancer invasion and attenuates the expression of BSP, OPN and MMP‑2.
Xu M, Jiang H, Wang H, Liu J, Liu B, Guo Z.
Oncol Rep · research-article; journal article · DOI 10.3892/or.2018.6504Therapeutic inhibition of CXC chemokine receptor 2 by SB225002 attenuates LPS-induced acute lung injury in mice.
Cao Q, Li B, Wang X, Sun K, Guo Y.
Arch Med Sci · research-article; journal article · DOI 10.5114/aoms.2017.64980SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1.
de Vasconcellos JF, Laranjeira AB, Leal PC, Bhasin MK, Zenatti PP, Nunes RJ, Yunes RA, Nowill AE, Libermann TA, Zerbini LF, Yunes JA.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0134783Molecular mechanisms of the antitumor activity of SB225002: a novel microtubule inhibitor.
Goda AE, Koyama M, Sowa Y, Elokely KM, Yoshida T, Kim BY, Sakai T.
Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2013.04.011SB225002 promotes mitotic catastrophe in chemo-sensitive and -resistant ovarian cancer cells independent of p53 status in vitro.
Du M, Qiu Q, Gruslin A, Gordon J, He M, Chan CC, Li D, Tsang BK.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0054572[Selective non-peptide CXCR2 antagonist SB225002 inhibits choroidal neovascularization in rat model].
Qu Y, Zhou F, Xu XY.
Zhonghua Yan Ke Za Zhi · research support, non-u.s. gov't; journal article; english abstractThe effects of the selective and non-peptide CXCR2 receptor antagonist SB225002 on acute and long-lasting models of nociception in mice.
Manjavachi MN, Quintão NL, Campos MM, Deschamps IK, Yunes RA, Nunes RJ, Leal PC, Calixto JB.
Eur J Pain · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejpain.2009.01.007The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice.
Bento AF, Leite DF, Claudino RF, Hara DB, Leal PC, Calixto JB.
J Leukoc Biol · research support, non-u.s. gov't; journal article · DOI 10.1189/jlb.0408231