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Publikationer som ChEBI hänvisar till för BRL-50481. Visa hela publikationsregistret

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Publications in the selection

9 hits

Bibliografisk träff 2020-04-09

PDE-7 Inhibitor BRL-50481 Reduces Neurodegeneration and Long-Term Memory Deficits in Mice Following Sevoflurane Exposure.

Chen Y, Li S, Zhong X, Kang Z, Chen R.

ACS Chem Neurosci · research support, non-u.s. gov't; journal article · DOI 10.1021/acschemneuro.0c00106

Bibliografisk träff 2019-11-07

Synthesis, biological screening, and molecular docking of quinazolinone and quinazolinethione as phosphodiesterase 7 inhibitors.

Elfeky SM, Sobahi TR, Gineinah MM, Ahmed NS.

Arch Pharm (Weinheim) · journal article · DOI 10.1002/ardp.201900211

Bibliografisk träff 2018-09-10

Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain.

Chłoń-Rzepa G, Ślusarczyk M, Jankowska A, Gawalska A, Bucki A, Kołaczkowski M, Świerczek A, Pociecha K, Wyska E, Zygmunt M, Kazek G, Sałat K, Pawłowski M.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2018.09.021

Bibliografisk träff 2018-02-04

Novel butanehydrazide derivatives of purine-2,6-dione as dual PDE4/7 inhibitors with potential anti-inflammatory activity: Design, synthesis and biological evaluation.

Chłoń-Rzepa G, Jankowska A, Ślusarczyk M, Świerczek A, Pociecha K, Wyska E, Bucki A, Gawalska A, Kołaczkowski M, Pawłowski M.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2018.01.068

Bibliografisk träff 2016-11-15

Phosphodiesterase-7 inhibition affects accumbal and hypothalamic thyrotropin-releasing hormone expression, feeding and anxiety behavior of rats.

Valdés-Moreno MI, Alcántara-Alonso V, Estrada-Camarena E, Mengod G, Amaya MI, Matamoros-Trejo G, de Gortari P.

Behav Brain Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbr.2016.11.027

Bibliografisk träff 2014-10-15

PDE4 and PDE5 regulate cyclic nucleotide contents and relaxing effects on carbachol-induced contraction in the bovine abomasum.

Kaneda T, Kido Y, Tajima T, Urakawa N, Shimizu K.

J Vet Med Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1292/jvms.14-0248

Bibliografisk träff 2013-11-13

A pharmacological network for lifespan extension in Caenorhabditis elegans.

Ye X, Linton JM, Schork NJ, Buck LB, Petrascheck M.

Aging Cell · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/acel.12163

Bibliografisk träff 2008-03-12

Effects of phosphodiesterase 7 inhibition by RNA interference on the gene expression and differentiation of human mesenchymal stem cell-derived osteoblasts.

Pekkinen M, Ahlström MEB, Riehle U, Huttunen MM, Lamberg-Allardt CJE.

Bone · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bone.2008.02.021

Bibliografisk träff 2004-09-15

Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes.

Smith SJ, Cieslinski LB, Newton R, Donnelly LE, Fenwick PS, Nicholson AG, Barnes PJ, Barnette MS, Giembycz MA.

Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.104.002246