Erastin synergizes with cisplatin via ferroptosis to inhibit ovarian cancer growth in vitro and in vivo.
Cheng Q, Bao L, Li M, Chang K, Yi X.
J Obstet Gynaecol Res · journal article · DOI 10.1111/jog.14779 PUBLICATION REGISTRY
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29 hitsFerroptosis is involved in the development of neuropathic pain and allodynia.
Wang H, Huo X, Han C, Ning J, Chen H, Li B, Liu J, Ma W, Li Q, Yu Y, Shi K.
Mol Cell Biochem · journal article · DOI 10.1007/s11010-021-04138-wTargeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in <i>EGFR</i>-activating mutant lung adenocarcinoma.
Zhang T, Sun B, Zhong C, Xu K, Wang Z, Hofman P, Nagano T, Legras A, Breadner D, Ricciuti B, Divisi D, Schmid RA, Peng RW, Yang H, Yao F.
Transl Lung Cancer Res · research-article; journal article · DOI 10.21037/tlcr-21-303Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.
Liu M, Fan Y, Li D, Han B, Meng Y, Chen F, Liu T, Song Z, Han Y, Huang L, Chang Y, Cao P, Nakai A, Tan K.
Mol Oncol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1002/1878-0261.12936Ferroptosis inducer erastin downregulates androgen receptor and its splice variants in castration‑resistant prostate cancer.
Yang Y, Liu T, Hu C, Xia H, Liu W, Chen J, Wu S, Jiang Y, Xu Y, Liu W, Zhao L.
Oncol Rep · journal article · DOI 10.3892/or.2021.7976Erastin induces ferroptosis via ferroportin-mediated iron accumulation in endometriosis.
Li Y, Zeng X, Lu D, Yin M, Shan M, Gao Y.
Hum Reprod · journal article · DOI 10.1093/humrep/deaa363Transferrin-based radiolabeled probe predicts the sensitivity of human renal cancer cell lines to ferroptosis inducer erastin.
Shibata Y, Yasui H, Higashikawa K, Kuge Y.
Biochem Biophys Rep · research-article; journal article · DOI 10.1016/j.bbrep.2021.100957Inhibition of SRSF9 enhances the sensitivity of colorectal cancer to erastin-induced ferroptosis by reducing glutathione peroxidase 4 expression.
Wang R, Su Q, Yin H, Wu D, Lv C, Yan Z.
Int J Biochem Cell Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.biocel.2021.105948Carnosic acid protects against ferroptosis in PC12 cells exposed to erastin through activation of Nrf2 pathway.
Cheng J, Xu T, Xun C, Guo H, Cao R, Gao S, Sheng W.
Life Sci · journal article · DOI 10.1016/j.lfs.2020.118905NCOA4-mediated ferritinophagy promotes ferroptosis induced by erastin, but not by RSL3 in HeLa cells.
Gryzik M, Asperti M, Denardo A, Arosio P, Poli M.
Biochim Biophys Acta Mol Cell Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbamcr.2020.118913Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis.
Kwon OS, Kwon EJ, Kong HJ, Choi JY, Kim YJ, Lee EW, Kim W, Lee H, Cha HJ.
Redox Biol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.redox.2020.101719Erastin-induced ferroptosis is a regulator for the growth and function of human pancreatic islet-like cell clusters.
Li XY, Leung PS.
Cell Regen · brief-report; journal article · DOI 10.1186/s13619-020-00055-3Neuroprotective effect of deferoxamine on erastininduced ferroptosis in primary cortical neurons.
Zhang Y, Fan BY, Pang YL, Shen WY, Wang X, Zhao CX, Li WX, Liu C, Kong XH, Ning GZ, Feng SQ, Yao X.
Neural Regen Res · research-article; journal article · DOI 10.4103/1673-5374.274344Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line.
Hoshino T, Yamakado H, Takahashi R, Matsuzawa SI.
FEBS Open Bio · research support, non-u.s. gov't; research-article; journal article · DOI 10.1002/2211-5463.12923Erastin triggers autophagic death of breast cancer cells by increasing intracellular iron levels.
Li M, Wang X, Lu S, He C, Wang C, Wang L, Wang X, Ge P, Song D.
Oncol Lett · research-article; journal article · DOI 10.3892/ol.2020.11918Erastin induces apoptotic and ferroptotic cell death by inducing ROS accumulation by causing mitochondrial dysfunction in gastric cancer cell HGC‑27.
Sun Y, Deng R, Zhang C.
Mol Med Rep · research-article; journal article · DOI 10.3892/mmr.2020.11376Regulation of GSK3β/Nrf2 signaling pathway modulated erastin-induced ferroptosis in breast cancer.
Wu X, Liu C, Li Z, Gai C, Ding D, Chen W, Hao F, Li W.
Mol Cell Biochem · journal article · DOI 10.1007/s11010-020-03821-8The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy.
Zhao Y, Li Y, Zhang R, Wang F, Wang T, Jiao Y.
Onco Targets Ther · review-article; review; journal article · DOI 10.2147/ott.s254995GDF15 knockdown promotes erastin-induced ferroptosis by decreasing SLC7A11 expression.
Chen L, Qiao L, Bian Y, Sun X.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2020.03.079Down-regulation of IDH2 sensitizes cancer cells to erastin-induced ferroptosis.
Kim H, Lee JH, Park JW.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2020.02.093Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma.
Yang Y, Luo M, Zhang K, Zhang J, Gao T, Connell DO, Yao F, Mu C, Cai B, Shang Y, Chen W.
Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-020-14324-xErastin Reverses ABCB1-Mediated Docetaxel Resistance in Ovarian Cancer.
Zhou HH, Chen X, Cai LY, Nan XW, Chen JH, Chen XX, Yang Y, Xing ZH, Wei MN, Li Y, Wang ST, Liu K, Shi Z, Yan XJ.
Front Oncol · research-article; journal article · DOI 10.3389/fonc.2019.01398Targeted exosome-encapsulated erastin induced ferroptosis in triple negative breast cancer cells.
Yu M, Gai C, Li Z, Ding D, Zheng J, Zhang W, Lv S, Li W.
Cancer Sci · research-article; journal article · DOI 10.1111/cas.14181ATF3 promotes erastin-induced ferroptosis by suppressing system Xc<sup>.</sup>
Wang L, Liu Y, Du T, Yang H, Lei L, Guo M, Ding HF, Zhang J, Wang H, Chen X, Yan C.
Cell Death Differ · research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/s41418-019-0380-zDiscovery and development of small molecule modulators targeting glutamine metabolism.
Li L, Meng Y, Li Z, Dai W, Xu X, Bi X, Bian J.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2018.11.066Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility.
Larraufie MH, Yang WS, Jiang E, Thomas AG, Slusher BS, Stockwell BR.
Bioorg Med Chem Lett · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2015.07.018Design and synthesis of Pictet-Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death.
Skouta R, Hayano M, Shimada K, Stockwell BR.
Bioorg Med Chem Lett · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2012.06.077RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels.
Yagoda N, von Rechenberg M, Zaganjor E, Bauer AJ, Yang WS, Fridman DJ, Wolpaw AJ, Smukste I, Peltier JM, Boniface JJ, Smith R, Lessnick SL, Sahasrabudhe S, Stockwell BR.
Nature · research-article; journal article · DOI 10.1038/nature05859Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells.
Dolma S, Lessnick SL, Hahn WC, Stockwell BR.
Cancer Cell · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1016/s1535-6108(03)00050-3