UBE2S activates NF-κB signaling by binding with IκBα and promotes metastasis of lung adenocarcinoma cells.
Ho JY, Lu HY, Cheng HH, Kuo YC, Lee YA, Cheng CH.
Cell Oncol (Dordr) · research-article; journal article · DOI 10.1007/s13402-021-00639-4 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för PS-1145. Visa hela publikationsregistret
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Publications in the selection
14 hits[Synergistic Effect of NF-κB Signaling Pathway Inhibitor and Oncolytic Measles Virus Vaccine Strain against Lung Cancer and Underlying Mechanisms].
Xia M, Meng G, Dong J.
Zhongguo Fei Ai Za Zhi · research-article; journal article · DOI 10.3779/j.issn.1009-3419.2021.102.14Cachexia induced by Yoshida ascites hepatoma in Wistar rats is not associated with inflammatory response in the spleen or brain.
Cernackova A, Mikova L, Horvathova L, Tillinger A, Mravec B.
J Neuroimmunol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jneuroim.2019.577068The anti-tumor function of the IKK inhibitor PS1145 and high levels of p65 and KLF4 are associated with the drug resistance in nasopharyngeal carcinoma cells.
Lung HL, Kan R, Chau WY, Man OY, Mak NK, Fong CH, Shuen WH, Tsao SW, Lung ML.
Sci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41598-019-48590-7Endothelial TFEB (Transcription Factor EB) Restrains IKK (IκB Kinase)-p65 Pathway to Attenuate Vascular Inflammation in Diabetic db/db Mice.
Song W, Zhang CL, Gou L, He L, Gong YY, Qu D, Zhao L, Jin N, Chan TF, Wang L, Tian XY, Luo JY, Huang Y.
Arterioscler Thromb Vasc Biol · research support, non-u.s. gov't; journal article · DOI 10.1161/atvbaha.119.312316The effect of an IκB-kinase-β(IKKβ) inhibitor on tobacco smoke-induced pulmonary inflammation.
Choi SI, Lee SY, Jung WJ, Lee SH, Lee EJ, Min KH, Hur GY, Lee SH, Lee SY, Kim JH, Shin C, Shim JJ, In KH, Kang KH, Lee MG.
Exp Lung Res · research support, non-u.s. gov't; journal article · DOI 10.1080/01902148.2016.1174749Administration of IκB-kinase inhibitor PS1145 enhances apoptosis in DMBA-induced tumor in male Wistar rats.
Rajmani RS, Gandham RK, Gupta SK, Sahoo AP, Singh PK, Saxena S, Kumar R, Chaturvedi U, Tiwari AK.
Cell Biol Int · research support, non-u.s. gov't; journal article · DOI 10.1002/cbin.10510Spatial control of bone formation using a porous polymer scaffold co-delivering anabolic rhBMP-2 and anti-resorptive agents.
Yu NY, Gdalevitch M, Murphy CM, Mikulec K, Peacock L, Fitzpatrick J, Cantrill LC, Ruys AJ, Cooper-White JJ, Little DG, Schindeler A.
Eur Cell Mater · research support, non-u.s. gov't; journal article · DOI 10.22203/ecm.v027a08Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells.
Khanbolooki S, Nawrocki ST, Arumugam T, Andtbacka R, Pino MS, Kurzrock R, Logsdon CD, Abbruzzese JL, McConkey DJ.
Mol Cancer Ther · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1158/1535-7163.mct-06-0075Interleukin 6, a nuclear factor-kappaB target, predicts resistance to docetaxel in hormone-independent prostate cancer and nuclear factor-kappaB inhibition by PS-1145 enhances docetaxel antitumor activity.
Domingo-Domenech J, Oliva C, Rovira A, Codony-Servat J, Bosch M, Filella X, Montagut C, Tapia M, Campás C, Dang L, Rolfe M, Ross JS, Gascon P, Albanell J, Mellado B.
Clin Cancer Res · clinical trial; research support, non-u.s. gov't; journal article · DOI 10.1158/1078-0432.ccr-05-2767Effects of IKK inhibitor PS1145 on NF-kappaB function, proliferation, apoptosis and invasion activity in prostate carcinoma cells.
Yemelyanov A, Gasparian A, Lindholm P, Dang L, Pierce JW, Kisseljov F, Karseladze A, Budunova I.
Oncogene · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1038/sj.onc.1209066The NF-kappaB pathway blockade by the IKK inhibitor PS1145 can overcome imatinib resistance.
Cilloni D, Messa F, Arruga F, Defilippi I, Morotti A, Messa E, Carturan S, Giugliano E, Pautasso M, Bracco E, Rosso V, Sen A, Martinelli G, Baccarani M, Saglio G.
Leukemia · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1038/sj.leu.2403998NF-kappaB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145.
Vodanovic-Jankovic S, Hari P, Jacobs P, Komorowski R, Drobyski WR.
Blood · comparative study; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1182/blood-2005-05-1820NF-kappa B as a therapeutic target in multiple myeloma.
Hideshima T, Chauhan D, Richardson P, Mitsiades C, Mitsiades N, Hayashi T, Munshi N, Dang L, Castro A, Palombella V, Adams J, Anderson KC.
J Biol Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.m200360200