Alpha-Tomatine Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated Macrophages.
Zhao B, Zhou B, Bao L, Yang Y, Guo K.
Inflammation · research support, non-u.s. gov't; journal article · DOI 10.1007/s10753-015-0154-9 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för tomatine. Visa hela publikationsregistret
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9 hitsDetoxification of α-tomatine by Cladosporium fulvum is required for full virulence on tomato.
Ökmen B, Etalo DW, Joosten MHAJ, Bouwmeester HJ, de Vos RCH, Collemare J, de Wit PJGM.
New Phytol · research support, non-u.s. gov't; journal article · DOI 10.1111/nph.12208α-Tomatine suppresses invasion and migration of human non-small cell lung cancer NCI-H460 cells through inactivating FAK/PI3K/Akt signaling pathway and reducing binding activity of NF-κB.
Shieh JM, Cheng TH, Shi MD, Wu PF, Chen Y, Ko SC, Shih YW.
Cell Biochem Biophys · journal article · DOI 10.1007/s12013-011-9152-1Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells.
Lee ST, Wong PF, Cheah SC, Mustafa MR.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0018915Tomatine adjuvantation of protective immunity to a major pre-erythrocytic vaccine candidate of malaria is mediated via CD8+ T cell release of IFN-gamma.
Heal KG, Taylor-Robinson AW.
J Biomed Biotechnol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1155/2010/834326Tomatine-containing green tomato extracts inhibit growth of human breast, colon, liver, and stomach cancer cells.
Friedman M, Levin CE, Lee SU, Kim HJ, Lee IS, Byun JO, Kozukue N.
J Agric Food Chem · journal article · DOI 10.1021/jf900364jAlpha-tomatine inactivates PI3K/Akt and ERK signaling pathways in human lung adenocarcinoma A549 cells: effect on metastasis.
Shih YW, Shieh JM, Wu PF, Lee YC, Chen YZ, Chiang TA.
Food Chem Toxicol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.fct.2009.05.011Protective effect of dietary tomatine against dibenzo[a,l]pyrene (DBP)-induced liver and stomach tumors in rainbow trout.
Friedman M, McQuistan T, Hendricks JD, Pereira C, Bailey GS.
Mol Nutr Food Res · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1002/mnfr.200700176alpha-Tomatine, the major saponin in tomato, induces programmed cell death mediated by reactive oxygen species in the fungal pathogen Fusarium oxysporum.
Ito S, Ihara T, Tamura H, Tanaka S, Ikeda T, Kajihara H, Dissanayake C, Abdel-Motaal FF, El-Sayed MA.
FEBS Lett · journal article · DOI 10.1016/j.febslet.2007.06.010