Steroidal sapogenins and glycosides from the rhizomes of Dioscorea bulbifera.
Liu H, Chou GX, Wu T, Guo YL, Wang SC, Wang CH, Wang ZT.
J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np900255h PUBLIKATIONSREGISTRET
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Publikationer i urvalet
50 träffarDiscovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification.
You QD, Li ZY, Huang CH, Yang Q, Wang XJ, Guo QL, Chen XG, He XG, Li TK, Chern JW.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm900469e7-Cycloalkylcamptothecin derivatives: Preparation and biological evaluation.
Li M, Jin W, Jiang C, Zheng C, Tang W, You T, Lou L.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.06.010Natural tanshinone-like heterocyclic-fused ortho-quinones from regioselective Diels-Alder reaction: synthesis and cytotoxicity evaluation.
Shen YD, Tian YX, Bu XZ, Gu LQ.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2009.04.016Cytotoxic asterosaponins capable of promoting polymerization of tubulin from the starfish Culcita novaeguineae.
Tang HF, Cheng G, Wu J, Chen XL, Zhang SY, Wen AD, Lin HW.
J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np8004858Benzyl ether-linked glucuronide derivative of 10-hydroxycamptothecin designed for selective camptothecin-based anticancer therapy.
Leu YL, Chen CS, Wu YJ, Chern JW.
J Med Chem · journal article · DOI 10.1021/jm701151cStudies on the chemical constituents and anticancer activity of Saxifraga stolonifera (L) Meeb.
Chen Z, Liu YM, Yang S, Song BA, Xu GF, Bhadury PS, Jin LH, Hu DY, Liu F, Xue W, Zhou X.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.10.072Bioactive triterpene glycosides from the sea cucumber Holothuria fuscocinerea.
Zhang SY, Yi YH, Tang HF.
J Nat Prod · journal article · DOI 10.1021/np060106tSteroidal saponins from Solanum nigrum.
Zhou X, He X, Wang G, Gao H, Zhou G, Ye W, Yao X.
J Nat Prod · journal article · DOI 10.1021/np060091zSynthesis and antitumor activity of 7-ethyl-9-alkyl derivatives of camptothecin.
Gao H, Zhang X, Chen Y, Shen H, Sun J, Huang M, Ding J, Li C, Lu W.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2005.02.072Cytotoxic sesquiterpenoids from Eupatorium chinense.
Yang SP, Huo J, Wang Y, Lou LG, Yue JM.
J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np0304159Selective phenolic acylation of 10-hydroxycamptothecin using poly (ethylene glycol) carboxylic acid.
Greenwald RB, Choe YH, Wu D.
Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(02)00926-5The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity.
Bom D, Curran DP, Kruszewski S, Zimmer SG, Thompson Strode J, Kohlhagen G, Du W, Chavan AJ, Fraley KA, Bingcang AL, Latus LJ, Pommier Y, Burke TG.
J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm000144oThe structural basis of camptothecin interactions with human serum albumin: impact on drug stability.
Burke TG, Mi Z.
J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00027a005Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs.
Wall ME, Wani MC, Nicholas AW, Manikumar G, Tele C, Moore L, Truesdale A, Leitner P, Besterman JM.
J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00070a013Ethyl substitution at the 7 position extends the half-life of 10-hydroxycamptothecin in the presence of human serum albumin.
Burke TG, Mi Z.
J Med Chem · journal article · DOI 10.1021/jm00069a020Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity.
Kingsbury WD, Boehm JC, Jakas DR, Holden KG, Hecht SM, Gallagher G, Caranfa MJ, McCabe FL, Faucette LF, Johnson RK.
J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00105a017A direct bioautographic tlc assay for compounds possessing antibacterial activity.
Hamburger MO, Cordell GA.
J Nat Prod · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/np50049a003Plant antitumor agents. 23. Synthesis and antileukemic activity of camptothecin analogues.
Wani MC, Nicholas AW, Wall ME.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00161a035Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogues.
Wani MC, Ronman PE, Lindley JT, Wall ME.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00179a016