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Publikationer i urvalet

50 träffar

Bibliografisk träff 2018-10-18

Glycyrrhetinic acid derivatives containing aminophosphonate ester species as multidrug resistance reversers that block the NF-κB pathway and cell proliferation.

Jin L, Zhang B, Hua S, Ji M, Huang X, Huang R, Wang H.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2018.10.025

Bibliografisk träff 2018-06-18

Lung cancer and matrix metalloproteinases inhibitors of polyphenols from Selaginella tamariscina with suppression activity of migration.

Wang CG, Yao WN, Zhang B, Hua J, Liang D, Wang HS.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2018.06.024

Bibliografisk träff 2018-02-13

Structure-based discovery of cytotoxic dimeric tetrahydroxanthones as potential topoisomerase I inhibitors from a marine-derived fungus.

Wu G, Qi X, Mo X, Yu G, Wang Q, Zhu T, Gu Q, Liu M, Li J, Li D.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2018.02.041

Bibliografisk träff 2017-08-15

Phthalazino[1,2-b]quinazolinones as p53 Activators: Cell Cycle Arrest, Apoptotic Response and Bak-Bcl-xl Complex Reorganization in Bladder Cancer Cells.

Zhang GH, Yuan JM, Qian G, Gu CX, Wei K, Mo DL, Qin JK, Peng Y, Zhou ZP, Pan CX, Su GF.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.6b01769

Bibliografisk träff 2017-05-12

Side chain-functionalized aniline-derived ursolic acid derivatives as multidrug resistance reversers that block the nuclear factor-kappa B (NF-κB) pathway and cell proliferation.

Huang RZ, Hua SX, Liao ZX, Huang XC, Wang HS.

Medchemcomm · research-article; journal article · DOI 10.1039/c7md00105c

Bibliografisk träff 2017-04-18

Design, combinatorial synthesis and biological evaluations of novel 3-amino-1'-((1-aryl-1H-1,2,3-triazol-5-yl)methyl)-2'-oxospiro[benzo[a] pyrano[2,3-c]phenazine-1,3'-indoline]-2-carbonitrile antitumor hybrid molecules.

Lu Y, Wang L, Wang X, Xi T, Liao J, Wang Z, Jiang F.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.04.040

Bibliografisk träff 2017-03-07

Synthesis and antitumor evaluation of 2,3-diarylbenzofuran derivatives on HeLa cells.

He GX, Yuan JM, Zhu HM, Wei K, Wang LY, Kong SL, Mo DL, Pan CX, Su GF.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2017.03.010

Bibliografisk träff 2016-11-03

Design, facile synthesis and biological evaluations of novel pyrano[3,2-a]phenazine hybrid molecules as antitumor agents.

Lu Y, Yan Y, Wang L, Wang X, Gao J, Xi T, Wang Z, Jiang F.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2016.10.068

Bibliografisk träff 2016-07-01

Synthesis and biological evaluation of 6-fluoro-3-phenyl-7-piperazinyl quinolone derivatives as potential topoisomerase I inhibitors.

Ge R, Zhao Q, Xie Z, Lu L, Guo Q, Li Z, Zhao L.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2016.06.054

Bibliografisk träff 2015-12-07

Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors.

Zhao Q, Xu X, Xie Z, Liu X, You Q, Guo Q, Zhong Y, Li Z.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2015.12.014

Bibliografisk träff 2015-08-06

Design and synthesis of 2-phenylnaphthalenoids and 2-phenylbenzofuranoids as DNA topoisomerase inhibitors and antitumor agents.

Hao H, Chen W, Zhu J, Lu C, Shen Y.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.07.048

Bibliografisk träff 2015-08-05

Synthesis and in vitro antitumor evaluation of betulin acid ester derivatives as novel apoptosis inducers.

Yang SJ, Liu MC, Xiang HM, Zhao Q, Xue W, Yang S.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.08.004

Bibliografisk träff 2015-04-04

Synthesis and biological evaluation of betulonic acid derivatives as antitumor agents.

Yang SJ, Liu MC, Zhao Q, Hu DY, Xue W, Yang S.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.04.006

Bibliografisk träff 2014-11-20

Synthesis of novel 10-hydroxycamptothecin derivatives utilizing topotecan hydrochloride as ortho-quinonemethide precursor.

Tan H, Wang G, Li J, Meng G, Liu Z, Dong M, Li Y, Ju D, Zhang Q.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2014.11.020

Bibliografisk träff 2014-07-17

Synthesis and biological evaluation of novel 6-chloro-quinazolin derivatives as potential antitumor agents.

Luo H, Yang S, Cai Y, Peng Z, Liu T.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2014.07.053

Bibliografisk träff 2013-08-11

Discovery, synthesis and biological evaluation of cycloprotoberberine derivatives as potential antitumor agents.

Li YB, Zhao WL, Wang YX, Zhang CX, Jiang JD, Bi CW, Tang S, Chen RX, Shao RG, Song DQ.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.07.026

Bibliografisk träff 2013-06-07

Synthesis and anticancer activities of 5,6,7-trimethoxy-N-phenyl(ethyl)-4-aminoquinazoline derivatives.

Zhang Y, Jin L, Xiang H, Wu J, Wang P, Hu D, Xue W, Yang S.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.05.043

Bibliografisk träff 2013-05-28

Semisynthesis, cytotoxic activity, and oral availability of new lipophilic 9-substituted camptothecin derivatives.

Rodriguez-Berna G, Cabañas MJ, Mangas-Sanjuán V, Gonzalez-Alvarez M, Gonzalez-Alvarez I, Abasolo I, Schwartz S, Bermejo M, Corma A.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/ml400125z

Bibliografisk träff 2013-04-15

Synthesis and antitumor activities of naturally occurring oleanolic acid triterpenoid saponins and their derivatives.

Liu Q, Liu H, Zhang L, Guo T, Wang P, Geng M, Li Y.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.04.016

Bibliografisk träff 2013-03-20

Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.

Zhou Y, Xu X, Sun Y, Wang H, Sun H, You Q.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2013.03.037

Bibliografisk träff 2012-10-23

Lanostanoids from fungi: a group of potential anticancer compounds.

Ríos JL, Andújar I, Recio MC, Giner RM.

J Nat Prod · research support, non-u.s. gov't; review; journal article · DOI 10.1021/np300412h

Bibliografisk träff 2012-10-06

Synthesis and cytotoxicity of novel ursolic acid derivatives containing an acyl piperazine moiety.

Liu MC, Yang SJ, Jin LH, Hu DY, Xue W, Song BA, Yang S.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2012.08.048

Bibliografisk träff 2012-09-26

Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Brunhofer G, Fallarero A, Karlsson D, Batista-Gonzalez A, Shinde P, Gopi Mohan C, Vuorela P.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2012.09.040

Bibliografisk träff 2012-07-26

Camptothecins in tumor homing via an RGD sequence mimetic.

Alloatti D, Giannini G, Vesci L, Castorina M, Pisano C, Badaloni E, Cabri W.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2012.07.061

Bibliografisk träff 2012-05-15

Synthesis and biological evaluation of new homocamptothecin analogs.

Luo Y, Yu S, Tong L, Huang Q, Lu W, Chen Y.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2012.05.002

Bibliografisk träff 2011-07-19

Synthesis, structure-activity relationship and biological evaluation of anticancer activity for novel N-substituted sophoridinic acid derivatives.

Li X, Zhao WL, Jiang JD, Ren KH, Du NN, Li YB, Wang YX, Bi CW, Shao RG, Song DQ.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.07.038

Bibliografisk träff 2011-05-05

Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors.

Wu WB, Ou JB, Huang ZH, Chen SB, Ou TM, Tan JH, Li D, Shen LL, Huang SL, Gu LQ, Huang ZS.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.04.059

Bibliografisk träff 2011-02-26

The solvolysis of topotecan in alcohols and acetic anhydride.

Li J, Wang G, Dong M, Zhang Q.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.02.080

Bibliografisk träff 2010-05-01

Diterpenoids from the feces of Trogopterus xanthipes.

Zhao J, Zhu HJ, Zhou XJ, Yang TH, Wang YY, Su J, Li Y, Cheng YX.

J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np900814s

Bibliografisk träff 2010-04-01

Polyhydroxysteroidal glycosides from the starfish Anthenea chinensis.

Ma N, Tang HF, Qiu F, Lin HW, Tian XR, Yao MN.

J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np9007188