The inducible nitric oxide synthase-inhibitor 1400W as a potential treatment for retinal diseases.
Schnichels S, Joachim SC.
Neural Regen Res · other; journal article · DOI 10.4103/1673-5374.300445 PUBLIKATIONSREGISTRET
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23 träffarCharacterization of ovine monocyte activity when cultured with Haemonchus contortus larvae in vitro.
Shepherd E, Greiner SP, Bowdridge SA.
Parasite Immunol · research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1111/pim.12773NOS2 inhibitor 1400W Induces Autophagic Flux and Influences Extracellular Vesicle Profile in Human Glioblastoma U87MG Cell Line.
Palumbo P, Lombardi F, Augello FR, Giusti I, Luzzi S, Dolo V, Cifone MG, Cinque B.
Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms20123010The impact of postsynaptic density 95 blocking peptide (Tat-NR2B9c) and an iNOS inhibitor (1400W) on proteomic profile of the hippocampus in C57BL/6J mouse model of kainate-induced epileptogenesis.
Tse K, Hammond D, Simpson D, Beynon RJ, Beamer E, Tymianski M, Salter MW, Sills GJ, Thippeswamy T.
J Neurosci Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/jnr.24441Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model.
Putra M, Sharma S, Gage M, Gasser G, Hinojo-Perez A, Olson A, Gregory-Flores A, Puttachary S, Wang C, Anantharam V, Thippeswamy T.
Neurobiol Dis · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.nbd.2019.03.031Nitric oxide synthase inhibitors 1400W and L-NIO inhibit angiogenesis pathway of colorectal cancer.
Gao Y, Zhou S, Xu Y, Sheng S, Qian SY, Huo X.
Nitric Oxide · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.niox.2018.12.008Inducible nitric oxide synthase inhibitor 1400W increases Na<sup>+</sup> ,K<sup>+</sup> -ATPase levels and activity and ameliorates mitochondrial dysfunction in Ctns null kidney proximal tubular epithelial cells.
Sumayao R, Newsholme P, McMorrow T.
Clin Exp Pharmacol Physiol · research support, non-u.s. gov't; journal article · DOI 10.1111/1440-1681.12998Inducible nitric oxide synthase inhibition by 1400W limits pain hypersensitivity in a neuropathic pain rat model.
Staunton CA, Barrett-Jolley R, Djouhri L, Thippeswamy T.
Exp Physiol · research support, non-u.s. gov't; journal article · DOI 10.1113/ep0867641400W ameliorates acute hypobaric hypoxia/reoxygenation-induced cognitive deficits by suppressing the induction of inducible nitric oxide synthase in rat cerebral cortex microglia.
Shi Q, Liu X, Wang N, Zheng X, Ran J, Liu Z, Fu J, Zheng J.
Behav Brain Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbr.2016.11.0391400W, a highly selective inducible nitric oxide synthase inhibitor is a potential disease modifier in the rat kainate model of temporal lobe epilepsy.
Puttachary S, Sharma S, Verma S, Yang Y, Putra M, Thippeswamy A, Luo D, Thippeswamy T.
Neurobiol Dis · research support, non-u.s. gov't; journal article · DOI 10.1016/j.nbd.2016.05.013Role of NOS2 in pulmonary injury and repair in response to bleomycin.
Guo C, Atochina-Vasserman E, Abramova H, George B, Manoj V, Scott P, Gow A.
Free Radic Biol Med · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.freeradbiomed.2015.10.417Antinociceptive effect of 1400 W, an inhibitor of inducible nitric oxide synthase, following hind paw incision in rats.
Gautam M, Kumar R, Prasoon P, Ray SB.
Nitric Oxide · journal article · DOI 10.1016/j.niox.2015.09.003Hypoxia-induced relaxation of porcine retinal arterioles in vitro depends on inducible NO synthase and EP4 receptor stimulation in the perivascular retina.
Oversø Hansen P, Kringelholt S, Simonsen U, Bek T.
Acta Ophthalmol · research support, non-u.s. gov't; journal article · DOI 10.1111/aos.126691400W reduces ischemia reperfusion injury in an ex-vivo porcine model of the donation after circulatory death kidney donor.
Hosgood SA, Yates PJ, Nicholson ML.
World J Transplant · research-article; journal article · DOI 10.5500/wjt.v4.i4.299N-[3-(aminomethyl)benzyl]acetamidine (1400 W) as a potential immunomodulatory agent.
Mertas A, Duliban H, Szliszka E, Machorowska-Pieniążek A, Król W.
Oxid Med Cell Longev · research-article; journal article · DOI 10.1155/2014/491214Selective anticancer agents suppress aging in Drosophila.
Danilov A, Shaposhnikov M, Plyusnina E, Kogan V, Fedichev P, Moskalev A.
Oncotarget · research support, non-u.s. gov't; research-article; journal article · DOI 10.18632/oncotarget.1272Inducible NOS inhibitor 1400W reduces hypoxia/re-oxygenation injury in rat lung.
Rus A, Castro L, Del Moral ML, Peinado A.
Redox Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1179/174329210x12650506623609Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
Fedorov R, Hartmann E, Ghosh DK, Schlichting I.
J Biol Chem · research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.m306030200Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3-(aminomethyl)benzyl]acetamidine.
Kankuri E, Vaali K, Knowles RG, Lähde M, Korpela R, Vapaatalo H, Moilanen E.
J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(24)29482-9Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice.
Muijsers RB, van Ark I, Folkerts G, Koster AS, van Oosterhout AJ, Postma DS, Nijkamp FP.
Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/sj.bjp.0704235N-(3-(aminomethyl)benzyl)acetamidine, an inducible nitric oxide synthase inhibitor, decreases colonic inflammation induced by trinitrobenzene sulphonic acid in rats.
Menchén LA, Colón AL, Moro MA, Leza JC, Lizasoain I, Menchén P, Alvarez E, Lorenzo P.
Life Sci · research support, non-u.s. gov't; journal article · DOI 10.1016/s0024-3205(01)01139-0Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Li H, Raman CS, Martásek P, Masters BS, Poulos TL.
Biochemistry · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/bi002658vProtective effect of N-(3-(aminomethyl)benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation.
Cárdenas A, De Alba J, Moro MA, Leza JC, Lorenzo P, Lizasoain I.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/s0014-2999(98)00458-0