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Publikationer i urvalet

8 träffar

Bibliografisk träff 2016-01-21

Tubastatin A, an HDAC6 inhibitor, alleviates stroke-induced brain infarction and functional deficits: potential roles of α-tubulin acetylation and FGF-21 up-regulation.

Wang Z, Leng Y, Wang J, Liao HM, Bergman J, Leeds P, Kozikowski A, Chuang DM.

Sci Rep · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/srep19626

Bibliografisk träff 2015-12-08

Exploration of the labeling of [11C]tubastatin A at the hydroxamic acid site with [11C]carbon monoxide.

Lu S, Zhang Y, Kalin JH, Cai L, Kozikowski AP, Pike VW.

J Labelled Comp Radiopharm · research support, n.i.h., intramural; research-article; journal article · DOI 10.1002/jlcr.3360

Bibliografisk träff 2015-04-25

Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes.

Choi SY, Ryu Y, Kee HJ, Cho SN, Kim GR, Cho JY, Kim HS, Kim IK, Jeong MH.

Vascul Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.vph.2015.04.006

Bibliografisk träff 2014-07-01

Selective inhibitor of histone deacetylase 6 (tubastatin A) suppresses proliferation of hepatitis C virus replicon in culture of human hepatocytes.

Kozlov MV, Kleymenova AA, Konduktorov KA, Malikova AZ, Kochetkov SN.

Biochemistry (Mosc) · research support, non-u.s. gov't; journal article · DOI 10.1134/s0006297914070050

Bibliografisk träff 2014-06-06

Involvement of transcription factor XBP1s in the resistance of HDAC6 inhibitor Tubastatin A to superoxidation via acetylation-mediated proteasomal degradation.

Zhang Y, Liu CM, Cao XC, Zang Y, Zhou YB, Li J.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2014.05.134

Bibliografisk träff 2014-01-01

Tubastatin A/ACY-1215 improves cognition in Alzheimer's disease transgenic mice.

Zhang L, Liu C, Wu J, Tao JJ, Sui XL, Yao ZG, Xu YF, Huang L, Zhu H, Sheng SL, Qin C.

J Alzheimers Dis · research support, non-u.s. gov't; journal article · DOI 10.3233/jad-140066

Bibliografisk träff 2013-03-27

Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects.

Vishwakarma S, Iyer LR, Muley M, Singh PK, Shastry A, Saxena A, Kulathingal J, Vijaykanth G, Raghul J, Rajesh N, Rathinasamy S, Kachhadia V, Kilambi N, Rajgopal S, Balasubramanian G, Narayanan S.

Int Immunopharmacol · journal article · DOI 10.1016/j.intimp.2013.03.016

Bibliografisk träff 2010-08-01

Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A.

Butler KV, Kalin J, Brochier C, Vistoli G, Langley B, Kozikowski AP.

J Am Chem Soc · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/ja102758v