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Publikationer som ChEBI hänvisar till för CHIR-090. Visa hela publikationsregistret

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Publications in the selection

8 hits

Bibliografisk träff 2016-08-15

Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606.

Richie DL, Takeoka KT, Bojkovic J, Metzger LE, Rath CM, Sawyer WS, Wei JR, Dean CR.

PLoS One · research-article; journal article · DOI 10.1371/journal.pone.0160918

Bibliografisk träff 2016-06-20

High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors.

Titecat M, Liang X, Lee CJ, Charlet A, Hocquet D, Lambert T, Pagès JM, Courcol R, Sebbane F, Toone EJ, Zhou P, Lemaitre N.

J Antimicrob Chemother · research-article; journal article · DOI 10.1093/jac/dkw210

Bibliografisk träff 2016-03-25

Untargeted Metabolomics To Ascertain Antibiotic Modes of Action.

Vincent IM, Ehmann DE, Mills SD, Perros M, Barrett MP.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.02109-15

Bibliografisk träff 2011-10-24

Mechanisms decreasing in vitro susceptibility to the LpxC inhibitor CHIR-090 in the gram-negative pathogen Pseudomonas aeruginosa.

Caughlan RE, Jones AK, Delucia AM, Woods AL, Xie L, Ma B, Barnes SW, Walker JR, Sprague ER, Yang X, Dean CR.

Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.05417-11

Bibliografisk träff 2010-12-20

Structure of the metal-dependent deacetylase LpxC from Yersinia enterocolitica complexed with the potent inhibitor CHIR-090 .

Cole KE, Gattis SG, Angell HD, Fierke CA, Christianson DW.

Biochemistry · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/bi101622a

Bibliografisk träff 2010-06-01

Antimicrobial activity of CHIR-090, an inhibitor of lipopolysaccharide biosynthesis, against the Burkholderia cepacia complex.

Bodewits K, Raetz CR, Govan JR, Campopiano DJ.

Antimicrob Agents Chemother · letter; research support, non-u.s. gov't; research support, n.i.h., extramural · DOI 10.1128/aac.01600-09

Bibliografisk träff 2007-11-19

Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding.

Barb AW, Jiang L, Raetz CR, Zhou P.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.0709412104

Bibliografisk träff 2007-03-03

Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coli.

Barb AW, McClerren AL, Snehelatha K, Reynolds CM, Zhou P, Raetz CR.

Biochemistry · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/bi6025165